Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | PAX3 | P23760 | 1/20 | 0.35 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867659 | 0.95 | KDM4E (0.39) | KDM4EPOLBHSD17B10MEN1TSHR | |
| SCHEMBL13443496 | 0.91 | POLB (0.42) | KDM4EPOLBHSD17B10MEN1TSHR | |
| SCHEMBL20052011 | 0.86 | KDM4E (0.47) | KDM4EMEN1TSHRKMT2ATK1 | |
| SCHEMBL20407788 | 0.86 | KDM4E (0.47) | KDM4EMEN1TSHRKMT2ATK1 | |
| SCHEMBL20052007 | 0.84 | KDM4E (0.36) | KDM4EMEN1TSHRKMT2AL3MBTL1 | |
| SCHEMBL18525302 | 0.83 | KDM4E (0.45) | KDM4EMEN1TSHRKMT2ATK1 | |
| SCHEMBL14867658 | 0.82 | KDM4E (0.35) | KDM4EMEN1TSHRKMT2AL3MBTL1 | |
| SCHEMBL14867654 | 0.81 | KDM4E (0.44) | KDM4EMEN1TSHRKMT2ATK1 | |
| SCHEMBL13443499 | 0.78 | L3MBTL1 (0.36) | KDM4EMEN1TSHRKMT2AL3MBTL1 | |
| SCHEMBL13443494 | 0.76 | KDM4E (0.45) | KDM4EMEN1TSHRKMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |