Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052032 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDRAB9ATSHRMAPK1 | |
| SCHEMBL20052026 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL20052025 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL20052029 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18000076 | 0.73 | KDM4E (0.39) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL27522004 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDRAB9ATSHR | |
| SCHEMBL20053011 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3820448 | 0.71 | ALDH1A1 (0.74) | ALDH1A1MAPTHPGDKDM4ERAB9A | |
| SCHEMBL5536756 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ESMN1; SMN2TSHR | |
| SCHEMBL29079448 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944723-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. (US) | 2018-04-17 | — | — | US | disclosed |