Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 0.46 |
| ▸ | CASP7 | P55210 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052419 | 1.00 | CASP3 (0.46) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20356004 | 0.92 | CASP3 (0.45) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052411 | 0.82 | CASP3 (0.66) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18472720 | 0.82 | CASP3 (0.66) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052415 | 0.80 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18472718 | 0.80 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052436 | 0.80 | CASP3 (0.56) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015955 | 0.80 | CASP3 (0.68) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL8259050 | 0.78 | CASP3 (0.60) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052382 | 0.76 | CASP3 (0.78) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |