Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462650 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL19944912 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL20355989 | 0.94 | SMN1; SMN2 (0.45) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL15462624 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL20052432 | 0.88 | CYP1A2 (0.49) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL15462640 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2CTSKCTSSPSENENCTSD | |
| SCHEMBL20052429 | 0.81 | CASP3 (0.54) | CTSKCTSSCTSDRENCYP2C9 | |
| SCHEMBL15462685 | 0.81 | CASP3 (0.54) | CTSKCTSSCTSDRENCYP2C9 | |
| SCHEMBL20052381 | 0.81 | CASP3 (0.54) | CTSKCTSSCTSDRENCYP2C9 | |
| SCHEMBL19944794 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |