Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 18/20 | 0.72 |
| ▸ | CASP7 | P55210 | 8/20 | 0.63 |
| ▸ | CASP1 | P29466 | 6/20 | 0.63 |
| ▸ | CASP9 | P55211 | 4/20 | 0.63 |
| ▸ | CASP4 | P49662 | 3/20 | 0.63 |
| ▸ | CASP5 | P51878 | 2/20 | 0.63 |
| ▸ | CASP6 | P55212 | 2/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.63 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.63 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462619 | 1.00 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20356163 | 1.00 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052421 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20355931 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462672 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462720 | 0.88 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052407 | 0.88 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20356114 | 0.88 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052366 | 0.88 | CASP3 (0.54) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20356111 | 0.88 | CASP3 (0.54) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |