Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 15/20 | 0.51 |
| ▸ | CASP7 | P55210 | 10/20 | 0.49 |
| ▸ | CASP1 | P29466 | 7/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | CASP9 | P55211 | 4/20 | 0.45 |
| ▸ | CASP4 | P49662 | 3/20 | 0.44 |
| ▸ | CASP5 | P51878 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.44 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 2/20 | 0.43 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944808 | 0.91 | PSMB5 (0.49) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL20052456 | 0.91 | CASP3 (0.62) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462695 | 0.90 | CASP3 (0.65) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL20355913 | 0.90 | CASP3 (0.65) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL20355912 | 0.90 | CASP3 (0.65) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL20052371 | 0.90 | CASP3 (0.65) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL19015746 | 0.84 | CASP3 (0.59) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL20052427 | 0.84 | CASP3 (0.61) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL19015922 | 0.82 | CASP3 (0.61) | CASP3CASP7CASP1PSMB5CASP9 | |
| SCHEMBL18782201 | 0.82 | CASP3 (0.61) | CASP3CASP7CASP1PSMB5CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |