Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010537 | 0.92 | GRM2 (0.69) | GRM2GRM3 | |
| SCHEMBL2003531 | 0.91 | GRM2 (0.68) | GRM2GRM3 | |
| SCHEMBL2007377 | 0.91 | GRM2 (0.68) | GRM2GRM3 | |
| SCHEMBL232547 | 0.91 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL1226471 | 0.91 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL2001339 | 0.86 | GRM2 (0.72) | GRM2GRM3 | |
| SCHEMBL1226470 | 0.86 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL232546 | 0.86 | GRM2 (0.75) | GRM2GRM3 | |
| SCHEMBL230418 | 0.84 | GRM2 (0.72) | GRM2GRM3 | |
| SCHEMBL4964584 | 0.84 | GRM2 (0.80) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960579-B2 | 2-amino-bicyclo [3.1.0] hexane-2,6-dicarboxylic ester derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-14 | — | — | US | claimed |
| US-8735397-B2 | Method for treating schizophrenia and related diseases | VANDERBILT UNIVERSITY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20110237602-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES | VANDERBILT UNIVERSITY (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237602-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES | GRM2, GRIA2, GRIK2 | GRM2 1/4885GRM3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.