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Sugi Predict / Compounds / SCHEMBL2010537

SCHEMBL2010537

SCHEMBL2010537

CCCCCC(CCCC)OC(=O)[C@@]1(N)[C@H]2[C@@H](C[C@H]1OCc1ccc(Cl)c(Cl)c1)[C@]2(F)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GRM2 Q14416 3/20 0.69
▸ GRM3 Q14832 3/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2007377 0.98 GRM2 (0.68) GRM2GRM3
SCHEMBL2003531 0.96 GRM2 (0.68) GRM2GRM3
SCHEMBL2005245 0.92 GRM2 (0.69) GRM2GRM3
SCHEMBL2001339 0.86 GRM2 (0.72) GRM2GRM3
SCHEMBL230418 0.86 GRM2 (0.72) GRM2GRM3
SCHEMBL232547 0.86 GRM2 (0.75) GRM2GRM3
SCHEMBL232546 0.86 GRM2 (0.75) GRM2GRM3
SCHEMBL1226471 0.86 GRM2 (0.75) GRM2GRM3
SCHEMBL1226470 0.86 GRM2 (0.75) GRM2GRM3
SCHEMBL4964584 0.84 GRM2 (0.80) GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960579-B2 2-amino-bicyclo [3.1.0] hexane-2,6-dicarboxylic ester derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2011-06-14 — — US claimed