Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986380 | 0.95 | HTR2C (0.38) | HTR2CHTR2BHTR2APTGDR2ADRB2 | |
| SCHEMBL18517278 | 0.92 | HTR2C (0.38) | HTR2CHTR2BHTR2APTGDR2ADRB2 | |
| SCHEMBL8934901 | 0.91 | FEN1 (0.38) | HTR2CHTR2BHTR2APTGDR2PTGDR | |
| SCHEMBL12733639 | 0.86 | HTR2C (0.42) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL172389 | 0.86 | HTR2C (0.42) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL10301654 | 0.85 | HTR2C (0.41) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL8961823 | 0.84 | HTR2C (0.34) | HTR2CHTR2BHTR2APTGDR2ADRB2 | |
| SCHEMBL14765795 | 0.83 | HTR2C (0.41) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL18712357 | 0.83 | HTR2C (0.41) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL12140870 | 0.82 | HTR2C (0.40) | HTR2CHTR2BHTR2AADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-20230007940-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCKP PATENT GMBH (DE) | 2023-01-12 | — | — | US | disclosed |
| US-11072742-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20210139777-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
| US-10934487-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| US-10894918-B2 | Liquid crystal medium containing polymerisable compounds | MERCK PATENT GMBH (DE) | 2021-01-19 | — | — | US | disclosed |
| US-20200291298-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| US-20190185754-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
| US-9944416-B2 | Filling device and use thereof for dispensing a fluid | MERCK PATENT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-9737854-B2 | Process for the purification of a liquid-crystal mixture | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |