Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 6/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052525 | 0.95 | HTR2C (0.41) | HTR2CHTR2BHTR2APTGDR2ADRB2 | |
| SCHEMBL8934901 | 0.94 | FEN1 (0.38) | HTR2CHTR2BHTR2APTGDR2FEN1 | |
| SCHEMBL19985581 | 0.87 | HTR2C (0.39) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL19986385 | 0.87 | FEN1 (0.37) | PTGDR2FEN1ALOX5APPTGDR | |
| SCHEMBL8961823 | 0.87 | HTR2C (0.34) | HTR2CHTR2BHTR2APTGDR2FEN1 | |
| SCHEMBL18517278 | 0.87 | HTR2C (0.38) | HTR2CHTR2BHTR2APTGDR2ADRB2 | |
| SCHEMBL19985588 | 0.85 | HTR2C (0.39) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL19986386 | 0.85 | PTGDR2 (0.36) | PTGDR2FEN1ALOX5APPTGDR | |
| SCHEMBL8934201 | 0.84 | PTGDR2 (0.41) | HTR2CHTR2BHTR2APTGDR2FEN1 | |
| SCHEMBL19986372 | 0.83 | PTGDR2 (0.40) | PTGDR2FEN1ALOX5APPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |