Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810226 | 0.82 | HTR2C (0.49) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20547110 | 0.81 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11791763 | 0.81 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11847386 | 0.77 | CYP3A4 (0.41) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10797345 | 0.77 | ALDH1A1 (0.53) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31346987 | 0.77 | SMN1; SMN2 (0.58) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11847374 | 0.76 | TSHR (0.41) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9573747 | 0.76 | HTR2C (0.49) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14372548 | 0.76 | SMN1; SMN2 (0.60) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10285807 | 0.75 | SMN1; SMN2 (0.52) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944623-B2 | Sterically hindered amine stabilizer | BASF SE (DE) | 2018-04-17 | — | — | US | disclosed |