Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596976 | 0.86 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL10291757 | 0.83 | — | — | |
| SCHEMBL172424 | 0.83 | — | — | |
| SCHEMBL172387 | 0.83 | — | — | |
| SCHEMBL24862296 | 0.76 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL9989406 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL21146097 | 0.73 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL20613668 | 0.73 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL599070 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL22882514 | 0.70 | SLC6A4 (0.32) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944633-B2 | Compounds and methods for the treatment of isocitrate dehydrogenase related diseases | THE BROAD INSTITUTE, INC. (US) | 2018-04-17 | — | — | US | disclosed |