Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24894004 | 0.87 | ALDH1A1 (0.33) | TSHRALDH1A1MAPK1 | |
| SCHEMBL20628212 | 0.84 | ALDH1A1 (0.32) | TSHRALDH1A1MAPK1 | |
| SCHEMBL18743385 | 0.84 | ALDH1A1 (0.32) | TSHRALDH1A1MAPK1 | |
| SCHEMBL24023982 | 0.84 | TSHR (0.61) | TSHRALDH1A1MAPK1ANPEPERAP2 | |
| SCHEMBL599070 | 0.82 | TSHR (0.35) | TSHRALDH1A1MAPK1 | |
| SCHEMBL19542937 | 0.80 | CYP3A4 (0.33) | TSHRCYP3A4CYP2D6NFKB1THPO | |
| SCHEMBL765779 | 0.79 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPRNPEP | |
| SCHEMBL13010113 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1MAPK1ANPEPERAP2 | |
| SCHEMBL28760216 | 0.79 | TSHR (0.33) | TSHRALDH1A1MAPK1CYP3A4CYP2D6 | |
| SCHEMBL5016256 | 0.79 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3783006-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2021-02-24 | — | — | EP | disclosed |
| EP-3444258-B1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2020-07-01 | — | — | EP | disclosed |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-20170283615-A1 | IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2017-10-05 | — | — | US | disclosed |
| EP-1416000-B1 | Process for preparing low molecular weight olefin (co)polymer and polymerizing catalyst used therefor | MITSUI CHEMICALS INC (JP) | 2011-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | TSHR 4573/4885ALDH1A1 420/4885MAPK1 3529/4885 |
| US-20170283615-A1 | IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM | PTAR1, LCAT, ANAPC7 | TSHR 4876/4885ALDH1A1 880/4885MAPK1 3180/4885 |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | TSHR 4573/4885ALDH1A1 420/4885MAPK1 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.