Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 16/20 | 0.62 |
| ▸ | MAOB | P27338 | 11/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.62 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 7/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133996 | 1.00 | KDM1A (0.62) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL16019172 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1524385 | 0.77 | KDM1A (0.87) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL7509163 | 0.77 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL17984427 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1800003 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL18023261 | 0.77 | KDM1A (1.00) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL13348123 | 0.77 | MEN1 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL21101634 | 0.77 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL13769735 | 0.77 | MEN1 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944589-B2 | Cycloproplyamine derivatives useful as inhibitors of histone demethylases KDM1A | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2018-04-17 | — | — | US | disclosed |