Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 9/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348123 | 1.00 | MEN1 (0.40) | MEN1MAPTKMT2AKDM1AMAOB | |
| SCHEMBL12808654 | 1.00 | MEN1 (0.40) | MEN1MAPTKMT2AKDM1AMAOB | |
| SCHEMBL18780010 | 0.84 | KDM1A (0.35) | MEN1MAPTKMT2AKDM1AMAOB | |
| SCHEMBL18536040 | 0.78 | ALDH1A1 (0.35) | MEN1MAPTKMT2AACHECYP19A1 | |
| SCHEMBL24133996 | 0.77 | KDM1A (0.62) | KDM1AMAOBMAOAKCNH2RCOR1 | |
| SCHEMBL20052941 | 0.77 | KDM1A (0.62) | KDM1AMAOBMAOAKCNH2RCOR1 | |
| SCHEMBL3673574 | 0.77 | HTR2A (0.52) | MAPTKDM1AACHEHTR2AHTR2C | |
| SCHEMBL11358152 | 0.76 | HPGD (0.47) | ACHEALDH1A1 | |
| SCHEMBL21355196 | 0.76 | DRD2 (0.47) | KDM1AMAOBCYP3A4 | |
| SCHEMBL24250707 | 0.76 | ALDH1A1 (0.38) | MEN1MAPTKMT2AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838710-B1 | HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2009-07-01 | — | — | EP | disclosed |