Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.79 |
| ▸ | ACACA | Q13085 | 1/20 | 0.79 |
| ▸ | ADORA2B | P29275 | 15/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935928 | 0.89 | ACACB (0.87) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL20651000 | 0.89 | ACACB (0.77) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14944943 | 0.89 | ACACB (1.00) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936242 | 0.88 | ACACB (0.85) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936299 | 0.88 | ACACB (0.84) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14944991 | 0.88 | ACACB (0.80) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936059 | 0.87 | ADORA2B (1.00) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14936183 | 0.87 | ACACB (0.89) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL16920241 | 0.87 | ACACB (0.82) | ACACBACACAADORA2BMEN1KMT2A | |
| SCHEMBL14944954 | 0.87 | ACACB (0.82) | ACACBACACAADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329919-A1 | ACC INHIBITORS AND USES THEREOF | Gilead Apollo, LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |