Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665061 | 0.91 | PTPRB (0.52) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL1114686 | 0.91 | PTPRB (0.52) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL13738958 | 0.91 | PTPRB (0.52) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL13739456 | 0.91 | PTPRB (0.52) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL18686907 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL20183231 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL15679446 | 0.79 | PTPRB (0.44) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL2976178 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL15664417 | 0.76 | PTPRB (0.43) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL15664415 | 0.76 | PTPRB (0.43) | ALDH1A1MAPTTP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |