Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 17/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | ACACA | Q13085 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20220430 | 1.00 | ADORA2B (0.54) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20651073 | 0.90 | ACACB (0.51) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14935929 | 0.84 | ACACB (0.72) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14936154 | 0.84 | ACACB (0.72) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14936544 | 0.84 | ACACB (0.72) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL20651003 | 0.77 | ADORA2B (0.56) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL21850054 | 0.77 | ADORA2B (0.70) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14936372 | 0.77 | ACACB (0.69) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL14945656 | 0.75 | ACACB (0.66) | ADORA2BACACBACACAMEN1KMT2A | |
| SCHEMBL21850065 | 0.74 | ADORA2B (0.66) | ADORA2BACACBACACAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |