Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052033 | 0.93 | ALDH1A1 (0.43) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL15753923 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20053011 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20052031 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20052028 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL23812449 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL16127475 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20052027 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL663178 | 0.77 | TDP1 (0.55) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL20052024 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944723-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. (US) | 2018-04-17 | — | — | US | disclosed |