Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412758 | 0.84 | SMN1; SMN2 (0.59) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL2413616 | 0.82 | NPSR1 (0.60) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL11569599 | 0.82 | NPSR1 (0.60) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL11570524 | 0.82 | NPSR1 (0.60) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL2416229 | 0.80 | SMN1; SMN2 (0.54) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL2417389 | 0.80 | SMN1; SMN2 (0.46) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL16922982 | 0.80 | SMN1; SMN2 (0.46) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL28508227 | 0.76 | KDM4E (0.41) | KMT2AHPGDEPHX1ALDH1A1NPC1 | |
| SCHEMBL14195897 | 0.73 | KMT2A (0.51) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 | |
| SCHEMBL14890449 | 0.73 | EPHX2 (0.56) | KMT2AHPGDEPHX1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |