Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26427828 | 0.90 | KDM4E (0.47) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL23422591 | 0.87 | KDM4E (0.49) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL23422676 | 0.85 | KDM4E (0.45) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL21757345 | 0.85 | KDM4E (0.48) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL27952715 | 0.84 | SMARCA2 (0.48) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL20053162 | 0.84 | KDM4E (0.47) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL21413789 | 0.82 | KDM4E (0.45) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL26427830 | 0.82 | KDM4E (0.45) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL20612838 | 0.82 | KDM4E (0.45) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL26427824 | 0.81 | USP30 (0.47) | KDM4EPKMUSP30GPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944658-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2018-04-17 | — | — | US | disclosed |