Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952715 | 0.88 | SMARCA2 (0.48) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL21757345 | 0.85 | KDM4E (0.48) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL20053160 | 0.85 | USP30 (0.46) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL26427824 | 0.84 | USP30 (0.47) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL20053161 | 0.84 | KDM4E (0.47) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL26427828 | 0.83 | KDM4E (0.47) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL26894524 | 0.83 | GPR119 (0.46) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL1385650 | 0.81 | SETD7 (0.51) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL23422591 | 0.81 | KDM4E (0.49) | KDM4EPKMUSP30GPR119JAK2 | |
| SCHEMBL8695092 | 0.80 | KDM4E (0.52) | KDM4EPKMUSP30GPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944658-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2018-04-17 | — | — | US | disclosed |