Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735097 | 0.81 | POLB (0.50) | HCRTR2TACR1 | |
| SCHEMBL12448072 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL15298999 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL12385957 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL24567517 | 0.79 | DPP4 (0.49) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL24449469 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL15943589 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL25463792 | 0.78 | PKM (0.47) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL22917045 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL14355655 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMCYP1A2CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| US-9944646-B2 | Bicyclic azaheterocyclobenzylamines as PI3K inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2018-04-17 | — | — | US | disclosed |