Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 14/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12031062 | 0.90 | PRMT5 (0.38) | PRMT5WDR77ADKXDHAHCY | |
| SCHEMBL8140442 | 0.90 | PRMT5 (0.38) | PRMT5WDR77ADKXDHAHCY | |
| SCHEMBL20052485 | 0.90 | PRMT5 (0.38) | PRMT5WDR77ADKXDHAHCY | |
| SCHEMBL19049971 | 0.86 | PRMT5 (0.37) | PRMT5WDR77ADKXDH | |
| SCHEMBL23171157 | 0.86 | PRMT5 (0.36) | PRMT5WDR77ADKXDHAHCY | |
| SCHEMBL19049923 | 0.82 | PRMT5 (0.37) | PRMT5WDR77ADKXDH | |
| SCHEMBL12031146 | 0.77 | PRMT5 (0.40) | PRMT5WDR77ADKXDHAHCY | |
| SCHEMBL19049922 | 0.77 | PRMT5 (0.43) | PRMT5WDR77ADKAHCYADORA2A | |
| SCHEMBL19050105 | 0.77 | PRMT5 (0.36) | PRMT5WDR77ADKXDH | |
| SCHEMBL19050106 | 0.75 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943538-B1 | 2′-methoxy substituted oligomeric compounds and compositions for use in gene modulations | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-17 | — | — | US | disclosed |