Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16777128 | 0.92 | SCN9A (0.45) | HRH3SCN9AACHEGABRA5 | |
| SCHEMBL15540422 | 0.92 | SCN9A (0.45) | HRH3SCN9AACHEGABRA5 | |
| SCHEMBL15539567 | 0.89 | ACHE (0.44) | GPR119LIPEACHE | |
| SCHEMBL20053648 | 0.88 | CYP2D6 (0.44) | HRH3CYP2D6SCN9AGPR119LIPE | |
| SCHEMBL15538438 | 0.87 | CHRM4 (0.42) | GPR119LIPEACHE | |
| SCHEMBL15539035 | 0.86 | SPHK2 (0.43) | SCN9AACHE | |
| SCHEMBL15539032 | 0.86 | SPHK2 (0.43) | SCN9AACHE | |
| SCHEMBL15539314 | 0.84 | SCN9A (0.46) | HRH3SCN9AACHEGABRA5 | |
| SCHEMBL15539316 | 0.84 | SCN9A (0.46) | HRH3SCN9AACHEGABRA5 | |
| SCHEMBL15537945 | 0.83 | HRH3 (0.42) | HRH3CYP2D6SCN9AGPR119LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |