Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 8/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 8/20 | 0.41 |
| ▸ | CPS1 | P31327 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848862 | 0.94 | GPR119 (0.56) | GPR119CYP4F2CYP4A11CPS1NR3C1 | |
| SCHEMBL15538261 | 0.92 | GPR119 (0.54) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15539460 | 0.92 | GPR119 (0.54) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15538264 | 0.92 | GPR119 (0.54) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL20053543 | 0.92 | GPR119 (0.54) | GPR119CYP4F2CYP4A11CPS1NR3C1 | |
| SCHEMBL18848988 | 0.92 | GPR119 (0.54) | GPR119CYP4F2CYP4A11CPS1NR3C1 | |
| SCHEMBL15537613 | 0.91 | GPR119 (0.56) | GPR119CYP4F2CYP4A11CPS1PARP15 | |
| SCHEMBL15538925 | 0.90 | GPR119 (0.57) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15537654 | 0.90 | GPR119 (0.57) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15537652 | 0.90 | GPR119 (0.57) | GPR119CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |