Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16777141 | 0.80 | HDAC4 (0.44) | CYP2D6OPRK1SSTR5 | |
| SCHEMBL15537803 | 0.80 | HDAC4 (0.44) | CYP2D6OPRK1SSTR5 | |
| SCHEMBL20053698 | 0.79 | SSTR5 (0.34) | CARM1PRMT6ACHEBACE1SSTR5 | |
| SCHEMBL15539383 | 0.76 | GRM3 (0.41) | SSTR5 | |
| SCHEMBL16777093 | 0.76 | GRM3 (0.41) | SSTR5 | |
| SCHEMBL15539256 | 0.76 | GRM3 (0.41) | SSTR5 | |
| SCHEMBL15540337 | 0.76 | SSTR5 (0.52) | CARM1PRMT6ACHEBACE1SSTR5 | |
| SCHEMBL16777015 | 0.75 | CHRM4 (0.46) | ACHEBACE1SSTR5 | |
| SCHEMBL21535007 | 0.73 | HRH3 (0.42) | SSTR5 | |
| SCHEMBL21534966 | 0.72 | HRH3 (0.42) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |