Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534966 | 0.99 | HRH3 (0.42) | HRH3SSTR5HPGDMAPK1MLYCD | |
| SCHEMBL21534964 | 0.91 | HRH3 (0.43) | HRH3SSTR5HPGDMAPK1MLYCD | |
| SCHEMBL16777093 | 0.91 | GRM3 (0.41) | HRH3SSTR5KMT2A | |
| SCHEMBL15539256 | 0.91 | GRM3 (0.41) | HRH3SSTR5KMT2A | |
| SCHEMBL15539383 | 0.91 | GRM3 (0.41) | HRH3SSTR5KMT2A | |
| SCHEMBL16777141 | 0.89 | HDAC4 (0.44) | HRH3SSTR5PTPN1LMNAPDK2 | |
| SCHEMBL15537803 | 0.89 | HDAC4 (0.44) | HRH3SSTR5PTPN1LMNAPDK2 | |
| SCHEMBL15540337 | 0.88 | SSTR5 (0.52) | SSTR5 | |
| SCHEMBL16777015 | 0.86 | CHRM4 (0.46) | SSTR5CNR1CNR2MEN1KMT2A | |
| SCHEMBL20053700 | 0.84 | SPHK1 (0.41) | SSTR5PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |