Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161747 | 0.75 | GRIA1 (0.58) | ALDH1A1POLBPKMTSHRNPSR1 | |
| SCHEMBL766545 | 0.73 | ALDH1A1 (0.42) | ALDH1A1PKMTSHRDNM1 | |
| SCHEMBL24303704 | 0.71 | ALDH1A1 (0.50) | ALDH1A1POLBPKMTSHRNPSR1 | |
| SCHEMBL24303119 | 0.69 | GRIA1 (0.45) | ALDH1A1TSHRNPSR1GRIA1DNM1 | |
| SCHEMBL24401280 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHRNPSR1GRIA1CYP2C9 | |
| SCHEMBL13585691 | 0.68 | ALDH1A1 (0.43) | ALDH1A1POLBPKMTSHRNPSR1 | |
| SCHEMBL13585687 | 0.68 | ALDH1A1 (0.43) | ALDH1A1POLBPKMTSHRNPSR1 | |
| SCHEMBL3217919 | 0.67 | ALDH1A1 (0.50) | ALDH1A1POLBPKMTSHRNPSR1 | |
| SCHEMBL13585600 | 0.67 | PMP22 (0.42) | ALDH1A1GRIA1ANPEP | |
| SCHEMBL13585191 | 0.67 | ALDH1A1 (0.42) | ALDH1A1POLBPKMTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |