Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | CPS1 | P31327 | 2/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803739 | 1.00 | PARP10 (0.44) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803878 | 0.98 | PARP10 (0.45) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803856 | 0.98 | PARP10 (0.45) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803807 | 0.92 | PARP10 (0.43) | PARP10PARP15CNR2SCN9AGPR119 | |
| SCHEMBL16803741 | 0.92 | PARP10 (0.40) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803738 | 0.91 | SPHK2 (0.45) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL20053737 | 0.91 | SPHK2 (0.45) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803938 | 0.90 | PARP10 (0.40) | PARP10PARP15CNR2SCN9APDK2 | |
| SCHEMBL16803884 | 0.90 | PARP10 (0.43) | PARP10PARP15CNR2SCN9AGPR119 | |
| SCHEMBL16803888 | 0.90 | PARP10 (0.43) | PARP10PARP15CNR2SCN9AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |