Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GYS1 | P13807 | 7/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803738 | 1.00 | SPHK2 (0.45) | SPHK2SPHK1PDK2ALDH1A1GYS1 | |
| SCHEMBL16803882 | 0.98 | SPHK1 (0.42) | SPHK2SPHK1PDK2ALDH1A1GYS1 | |
| SCHEMBL16803885 | 0.98 | SPHK1 (0.42) | SPHK2SPHK1PDK2ALDH1A1GYS1 | |
| SCHEMBL16803826 | 0.95 | PDK2 (0.46) | SPHK2SPHK1PDK2ALDH1A1GYS1 | |
| SCHEMBL16803817 | 0.94 | PDK2 (0.47) | SPHK2SPHK1PDK2ALDH1A1GYS1 | |
| SCHEMBL16803857 | 0.91 | PDK2 (0.45) | SPHK2SPHK1PDK2ALDH1A1PARP10 | |
| SCHEMBL16803877 | 0.91 | PDK2 (0.45) | SPHK2SPHK1PDK2ALDH1A1PARP10 | |
| SCHEMBL16803739 | 0.91 | PARP10 (0.44) | SPHK2SPHK1PDK2GYS1PARP10 | |
| SCHEMBL20053733 | 0.91 | PARP10 (0.44) | SPHK2SPHK1PDK2GYS1PARP10 | |
| SCHEMBL16803785 | 0.90 | SPHK2 (0.51) | SPHK2SPHK1PDK2ALDH1A1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |