Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537650 | 0.89 | SPHK1 (0.44) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539929 | 0.89 | SPHK1 (0.44) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539930 | 0.89 | SPHK1 (0.44) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL20053596 | 0.86 | NPSR1 (0.48) | SPHK1SPHK2HRH3CNR2NPSR1 | |
| SCHEMBL15539106 | 0.85 | SPHK2 (0.51) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539080 | 0.85 | SPHK2 (0.51) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539078 | 0.85 | SPHK2 (0.51) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539131 | 0.84 | SPHK2 (0.49) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15539132 | 0.84 | SPHK2 (0.49) | SPHK1SPHK2POLBHRH3 | |
| SCHEMBL15540017 | 0.83 | SPHK1 (0.46) | SPHK1SPHK2POLBHRH3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |