Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803808 | 0.90 | L3MBTL1 (0.48) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL20053752 | 0.86 | SPHK1 (0.47) | NPSR1SPHK2SPHK1HRH3CNR2 | |
| SCHEMBL16803729 | 0.85 | SPHK2 (0.51) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803785 | 0.85 | SPHK2 (0.51) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803898 | 0.84 | SPHK2 (0.50) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803859 | 0.83 | SPHK1 (0.49) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803860 | 0.83 | SPHK1 (0.49) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803773 | 0.83 | SPHK2 (0.47) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803732 | 0.83 | SPHK1 (0.49) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 | |
| SCHEMBL16803804 | 0.83 | ALDH1A1 (0.47) | NPSR1ALDH1A1SPHK2SPHK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |