Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850220 | 1.00 | KCNH2 (0.33) | KCNH2EPHX1 | |
| SCHEMBL22272085 | 0.81 | ADH1B (0.34) | — | |
| SCHEMBL20461226 | 0.74 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL21765675 | 0.73 | — | — | |
| SCHEMBL20053908 | 0.73 | ADH1B (0.32) | — | |
| SCHEMBL30041132 | 0.69 | — | — | |
| SCHEMBL30042408 | 0.69 | — | — | |
| SCHEMBL21850193 | 0.69 | EPHX2 (0.31) | — | |
| SCHEMBL20461153 | 0.69 | MAPT (0.36) | — | |
| SCHEMBL21850224 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357921-A2 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | Sunesis Pharmaceuticals, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3080103-B1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN MA INC (US) | 2018-04-18 | — | — | EP | disclosed |