Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054055 | 0.81 | IKBKE (0.43) | BTK | |
| SCHEMBL16793965 | 0.79 | BTK (0.45) | BTK | |
| SCHEMBL20054043 | 0.78 | BTK (0.43) | BTK | |
| SCHEMBL20461122 | 0.74 | — | — | |
| SCHEMBL20054053 | 0.73 | — | — | |
| SCHEMBL16793990 | 0.72 | AAK1 (0.40) | BTK | |
| SCHEMBL16814204 | 0.71 | BTK (0.43) | BTK | |
| SCHEMBL16794179 | 0.70 | BTK (0.42) | BTK | |
| Hydrochloric Acid SCHEMBL16794342 | 0.70 | BTK (0.43) | BTK | |
| SCHEMBL16794158 | 0.70 | BTK (0.61) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080103-B1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN MA INC (US) | 2018-04-18 | — | — | EP | disclosed |