Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.40 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113143 | 1.00 | SCN10A (0.40) | SCN10ANLNS1PR4S1PR1S1PR3 | |
| SCHEMBL16407731 | 0.89 | SCN10A (0.44) | SCN10ANLNS1PR4S1PR1S1PR3 | |
| SCHEMBL19388443 | 0.86 | SCN10A (0.40) | SCN10A | |
| SCHEMBL15116602 | 0.86 | SCN10A (0.40) | SCN10A | |
| SCHEMBL15105893 | 0.82 | SCN10A (0.39) | SCN10ANLNSCN5A | |
| SCHEMBL15105760 | 0.82 | HPGDS (0.42) | SCN10ANLN | |
| SCHEMBL15116606 | 0.82 | SNCA (0.32) | — | |
| SCHEMBL19388632 | 0.82 | SNCA (0.32) | — | |
| SCHEMBL20054450 | 0.82 | NLN (0.39) | SCN10ANLN | |
| SCHEMBL15116770 | 0.82 | NLN (0.39) | SCN10ANLN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |