Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116600 | 1.00 | AAK1 (0.42) | AAK1PRMT5WDR77SSTR3LPL | |
| SCHEMBL15116616 | 0.90 | AAK1 (0.43) | AAK1PRMT5WDR77SSTR3LPL | |
| SCHEMBL16358805 | 0.90 | AAK1 (0.44) | AAK1PRMT5WDR77SSTR3LPL | |
| SCHEMBL20054513 | 0.88 | PRMT5 (0.38) | AAK1PRMT5WDR77SSTR3DGAT1 | |
| SCHEMBL15116590 | 0.88 | PRMT5 (0.38) | AAK1PRMT5WDR77SSTR3DGAT1 | |
| SCHEMBL20054377 | 0.86 | SSTR3 (0.44) | AAK1SSTR3GSK3BDYRK1AHDAC1 | |
| SCHEMBL15116811 | 0.86 | SSTR3 (0.44) | AAK1SSTR3GSK3BDYRK1AHDAC1 | |
| SCHEMBL19414754 | 0.85 | SSTR3 (0.46) | AAK1SSTR3GSK3BDYRK1AHDAC1 | |
| SCHEMBL12117653 | 0.85 | SSTR3 (0.46) | AAK1SSTR3GSK3BDYRK1AHDAC1 | |
| SCHEMBL15116761 | 0.82 | SSTR3 (0.42) | AAK1SSTR3GSK3BDYRK1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |