Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116590 | 1.00 | PRMT5 (0.38) | PRMT5WDR77AAK1NR1I2SSTR3 | |
| SCHEMBL15116835 | 0.89 | NR1I2 (0.43) | AAK1NR1I2SSTR3KDM4EGLA | |
| SCHEMBL20054411 | 0.88 | AAK1 (0.42) | PRMT5WDR77AAK1SSTR3USP30 | |
| SCHEMBL15116600 | 0.88 | AAK1 (0.42) | PRMT5WDR77AAK1SSTR3USP30 | |
| SCHEMBL15116836 | 0.85 | SSTR3 (0.40) | AAK1NR1I2SSTR3KDM4EGLA | |
| SCHEMBL20054535 | 0.85 | SSTR3 (0.40) | AAK1NR1I2SSTR3KDM4EGLA | |
| SCHEMBL15114363 | 0.85 | NR1I2 (0.42) | AAK1NR1I2SSTR3KDM4EGLA | |
| SCHEMBL15114362 | 0.81 | LPL (0.34) | NR1I2APPHDAC6 | |
| SCHEMBL15105782 | 0.79 | AAK1 (0.46) | PRMT5WDR77AAK1NR1I2SSTR3 | |
| SCHEMBL15105781 | 0.79 | AAK1 (0.46) | PRMT5WDR77AAK1NR1I2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |