Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392486 | 0.92 | KMT2A (0.38) | KMT2AMEN1MAPK1CTSLAPLNR | |
| SCHEMBL19920575 | 0.85 | KMT2A (0.35) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL15114559 | 0.85 | TSHR (0.35) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL15116717 | 0.85 | TSHR (0.37) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL2716648 | 0.85 | KMT2A (0.36) | KMT2AMEN1MAPK1CTSLAPLNR | |
| SCHEMBL4742076 | 0.85 | KMT2A (0.36) | KMT2AMEN1MAPK1CTSLAPLNR | |
| SCHEMBL2746255 | 0.84 | MAPT (0.35) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL16359134 | 0.84 | TSHR (0.34) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL15114191 | 0.84 | CTSL (0.36) | TSHRFSHRKMT2AMEN1MAPK1 | |
| SCHEMBL2087505 | 0.83 | GAA (0.36) | KMT2AMEN1MAPK1CTSLAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |