Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116775 | 1.00 | SSTR3 (0.40) | SSTR3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL16409154 | 0.96 | SSTR3 (0.41) | SSTR3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL15116767 | 0.92 | GABRA1 (0.42) | SSTR3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20054356 | 0.92 | SSTR3 (0.39) | SSTR3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL15116773 | 0.92 | SSTR3 (0.39) | SSTR3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL20054377 | 0.89 | SSTR3 (0.44) | SSTR3GABRB1GABRB2HDAC1AAK1 | |
| SCHEMBL15116811 | 0.89 | SSTR3 (0.44) | SSTR3GABRB1GABRB2HDAC1AAK1 | |
| SCHEMBL12117653 | 0.88 | SSTR3 (0.46) | SSTR3GABRB1GABRB2HDAC1AAK1 | |
| SCHEMBL19414754 | 0.88 | SSTR3 (0.46) | SSTR3GABRB1GABRB2HDAC1AAK1 | |
| SCHEMBL15116447 | 0.86 | SSTR3 (0.47) | SSTR3GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |