Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055405 | 0.77 | TRPV1 (0.46) | PDE10ASCN10ASCN5AMASP2 | |
| SCHEMBL2562957 | 0.76 | PDE10A (0.64) | PDE10AKLK1KLK5MASP2 | |
| SCHEMBL25303515 | 0.73 | SCN2A (0.55) | PDE10ASCN10ASCN5A | |
| SCHEMBL12648128 | 0.73 | NLN (0.41) | PDE10ASCN10ASCN5A | |
| SCHEMBL19388645 | 0.73 | SCN10A (0.40) | SCN10ASCN5A | |
| SCHEMBL15114359 | 0.73 | SCN10A (0.40) | SCN10ASCN5A | |
| SCHEMBL20054552 | 0.72 | NLN (0.43) | PDE10ASCN10ASCN5A | |
| Bromide SCHEMBL16210189 | 0.72 | SCN2A (0.54) | PDE10ASCN10ASCN5A | |
| Bromide SCHEMBL25307759 | 0.72 | SCN10A (0.56) | SCN10ASCN5A | |
| SCHEMBL20054471 | 0.71 | NLN (0.42) | PDE10ASCN10ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |