Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.37 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648128 | 0.97 | NLN (0.41) | NLNSCN10APDE10ASCN5APADI1 | |
| SCHEMBL20054471 | 0.95 | NLN (0.42) | NLNSCN10APDE10ASCN5APYGL | |
| SCHEMBL20054430 | 0.87 | AAK1 (0.41) | NLN | |
| SCHEMBL20054454 | 0.82 | SCN10A (0.36) | NLNSCN10APDE10ASCN5APYGL | |
| SCHEMBL20054547 | 0.81 | CYP2A6 (0.38) | NLNSCN10APYGLCYP11B1CYP11B2 | |
| SCHEMBL20054582 | 0.78 | SHBG (0.40) | SCN10APDE10ASCN5A | |
| SCHEMBL20054383 | 0.78 | PDE10A (0.37) | SCN10APDE10ASCN5A | |
| SCHEMBL20054554 | 0.77 | AAK1 (0.46) | PDE10A | |
| SCHEMBL20054529 | 0.77 | AAK1 (0.46) | PDE10A | |
| SCHEMBL20055405 | 0.77 | TRPV1 (0.46) | SCN10APDE10ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |