Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | EIF2S1 | P05198 | 2/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114299 | 1.00 | CNR1 (0.35) | CNR1CNR2ARADORA1CASP1 | |
| SCHEMBL15114300 | 1.00 | CNR1 (0.35) | CNR1CNR2ARADORA1CASP1 | |
| SCHEMBL20054354 | 1.00 | CNR1 (0.35) | CNR1CNR2ARADORA1CASP1 | |
| SCHEMBL20054353 | 1.00 | CNR1 (0.35) | CNR1CNR2ARADORA1CASP1 | |
| SCHEMBL20054451 | 0.83 | ADORA1 (0.32) | CNR1CNR2ADORA1 | |
| SCHEMBL15114308 | 0.83 | ADORA1 (0.32) | CNR1CNR2ADORA1 | |
| SCHEMBL19388431 | 0.83 | FAAH (0.33) | CNR1CNR2ADORA1PDE2AROCK1 | |
| SCHEMBL15113745 | 0.83 | FAAH (0.33) | CNR1CNR2ADORA1PDE2AROCK1 | |
| SCHEMBL15113728 | 0.83 | PRCP (0.34) | CNR1CNR2ADORA1 | |
| SCHEMBL20054322 | 0.83 | PRCP (0.34) | CNR1CNR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |