Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 2/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 9/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116841 | 1.00 | NLN (0.46) | NLNSCN10AHDAC1KCNH2SCN1A | |
| SCHEMBL19388595 | 1.00 | NLN (0.46) | NLNSCN10AHDAC1KCNH2SCN1A | |
| SCHEMBL19414850 | 0.93 | NLN (0.46) | NLNSCN10AKCNH2SCN1ASCN5A | |
| SCHEMBL1315025 | 0.93 | NLN (0.46) | NLNSCN10AKCNH2SCN1ASCN5A | |
| SCHEMBL19388433 | 0.88 | NLN (0.39) | NLNHDAC1HDAC3 | |
| SCHEMBL15116782 | 0.88 | NLN (0.39) | NLNHDAC1HDAC3 | |
| SCHEMBL19388554 | 0.85 | AAK1 (0.47) | NLNSCN10A | |
| SCHEMBL20054422 | 0.85 | AAK1 (0.47) | NLNSCN10A | |
| SCHEMBL15116784 | 0.85 | AAK1 (0.47) | NLNSCN10A | |
| SCHEMBL16407731 | 0.85 | SCN10A (0.44) | NLNSCN10AKCNH2SCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |