SCHEMBL2005451

SCHEMBL2005451

O=C(CC(=O)c1ccc(C(=O)CC(=O)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.94
KMT2A Q03164 3/20 0.94
HPGD P15428 3/20 0.94
MAPK1 P28482 3/20 0.94
MAPT P10636 3/20 0.94
CES1 P23141 3/20 0.94
CYP3A4 P08684 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
ALOX15 P16050 2/20 0.94
SMN1; SMN2 Q16637 2/20 0.94
KDM4E B2RXH2 1/20 0.94
NPC1 O15118 3/20 0.78
RAB9A P51151 2/20 0.78
PLOD2 O00469 2/20 0.71
ALDH1A1 P00352 2/20 0.71
HIF1A Q16665 2/20 0.71
PLOD3 O60568 1/20 0.71
CYP1A2 P05177 1/20 0.71
CYP2D6 P10635 1/20 0.71
CYP2C9 P11712 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL39582 0.97 MEN1 (1.00) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL10356288 0.97 MEN1 (1.00) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL1704711 0.97 MEN1 (1.00) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL531257 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL21597905 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL9493785 0.94 MAPT (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL6598370 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL6249492 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL1628627 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT
Dibenzoylmethane SCHEMBL11588084 0.94 MEN1 (0.94) MEN1KMT2AHPGDMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP claimed
CN-115449240-B Blue light shielding material and preparation method and application thereof 包头稀土研究院 2023-06-02 CN disclosed
CN-115449240-A Blue light shielding material and preparation method and application thereof 包头稀土研究院 2022-12-09 CN disclosed
US-7964022-B2 Method and apparatus for selective capture of gas phase analytes using metal β-diketonate polymers BATTELLE MEMORIAL INSTITUTE (US) 2011-06-21 US disclosed
US-7964028-B2 Method and apparatus for selective capture of gas phase analytes using metal β-diketonate polymers BATTELLE MEMORIAL INSTITUTE (US) 2011-06-21 US disclosed
US-20100203652-A1 Method and apparatus for selective capture of gas phase analytes using metal beta-diketonate polymers BATTELLE MEMORIAL INSTITUTE (US) 2010-08-12 US disclosed
US-20100058924-A1 METHOD AND APPARATUS FOR SELECTIVE CAPTURE OF GAS PHASE ANALYTES USING METAL BETA-DIKETONATE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 2010-03-11 US disclosed
EP-0046161-B1 STABILIZED POLYVINYLHALIDE RESIN PHOENIX CHEMICAL CORPORATION (US) 1986-11-12 EP disclosed
US-4506001-A Photographic recording material containing novel coordination polymer FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US disclosed
US-4371651-A PHOTOSTABILITY, HEAT RESISTANCE PHOENIX CHEMICAL CORPORATION (US) 1983-02-01 US disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP disclosed