Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15116772 | 1.00 | AAK1 (0.66) | AAK1KMT2ASCN10AMLKLTRPV1 | |
| SCHEMBL15116751 | 0.88 | AAK1 (0.52) | AAK1KMT2ASCN10ALCK | |
| SCHEMBL20054545 | 0.87 | AAK1 (0.64) | AAK1SCN10AMLKLTRPV1LCK | |
| SCHEMBL15116826 | 0.87 | AAK1 (0.64) | AAK1SCN10AMLKLTRPV1LCK | |
| SCHEMBL17494112 | 0.85 | AAK1 (0.69) | AAK1 | |
| SCHEMBL15116808 | 0.85 | AAK1 (0.49) | AAK1KMT2ASCN10ALCK | |
| SCHEMBL20221198 | 0.85 | AAK1 (0.49) | AAK1KMT2ASCN10ALCK | |
| SCHEMBL15116842 | 0.83 | AAK1 (0.48) | AAK1KMT2ASCN10ALCK | |
| SCHEMBL26502047 | 0.82 | AAK1 (0.46) | AAK1KMT2ALCK | |
| SCHEMBL15116805 | 0.81 | AAK1 (0.47) | AAK1KMT2ASCN10ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |