Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287811 | 0.83 | KDM4E (0.61) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL1812108 | 0.81 | ALDH1A1 (0.45) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL319270 | 0.81 | MAPT (0.49) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL15863495 | 0.81 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL1874614 | 0.81 | KDM4E (0.59) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL20221424 | 0.81 | KDM4E (0.44) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL13819934 | 0.80 | KDM4E (0.43) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL25184346 | 0.79 | ATM (0.45) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL7001524 | 0.79 | KDM4E (0.42) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL18694922 | 0.79 | MAPT (0.47) | KDM4EMAPTALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |