Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241360 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1PDE3A | |
| SCHEMBL20904217 | 0.81 | PTGS2 (0.74) | PTGS2PTGS1PDE3A | |
| SCHEMBL11099601 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1PDE3A | |
| SCHEMBL9123885 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1PDE3A | |
| SCHEMBL9181299 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1PDE3A | |
| SCHEMBL13890455 | 0.79 | PTGS2 (0.80) | PTGS2PTGS1PDE3A | |
| Mofezolac SCHEMBL151701 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1PDE3A | |
| SCHEMBL9124091 | 0.78 | PTGS2 (0.74) | PTGS2PTGS1PDE3A | |
| SCHEMBL9122616 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1PDE3A | |
| SCHEMBL13220681 | 0.78 | PTGS2 (0.69) | PTGS2PTGS1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2863921-B1 | POLYMER-NSAID CONJUGATE | POLYACTIVA PTY LTD (AU) | 2018-04-18 | — | — | EP | disclosed |