Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13274038 | 0.91 | MEN1 (0.36) | MEN1KMT2ACYP2C9RAB9AGAA | |
| SCHEMBL12846960 | 0.85 | MME (0.45) | MEN1KMT2AALDH1A1ADRB2HTT | |
| SCHEMBL7432517 | 0.82 | ALDH1A1 (0.34) | ALDH1A1ADRB2HTTMMELMNA | |
| SCHEMBL880578 | 0.82 | ALDH1A1 (0.34) | ALDH1A1ADRB2HTTMMELMNA | |
| SCHEMBL12783465 | 0.82 | ALDH1A1 (0.34) | ALDH1A1ADRB2HTTMMELMNA | |
| SCHEMBL16509280 | 0.82 | KMT2A (0.36) | MEN1KMT2ACYP1A2 | |
| SCHEMBL30325251 | 0.81 | MME (0.42) | MEN1KMT2AMME | |
| SCHEMBL15116428 | 0.80 | SMN1; SMN2 (0.34) | ALDH1A1ADRB2HTTMMECETP | |
| SCHEMBL23573562 | 0.80 | MME (0.37) | ALDH1A1ADRB2HTTMMELMNA | |
| SCHEMBL19388214 | 0.79 | CETP (0.34) | ALDH1A1ADRB2HTTMMELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-2300007-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | TARO PHARMACEUTICALS INC (CA) | 2018-04-18 | — | — | EP | disclosed |