Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153059 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL17368119 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL7123996 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL18660486 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL19129772 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL19129723 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL23288110 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL2159722 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL21938541 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA | |
| SCHEMBL5365686 | 1.00 | CA2 (0.41) | CA2CA1CA9MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |